As unmanned aircraft systems multiply with astonishing rapidity and their contribution to earth surveillance and the treatment of emergency situations increases in parallel to the commercial, homeland security and military applications, there is a pressing need to ensure the security and environmental safety of this increased traffic. This seminar brought together representatives of the U.S. Administration and Congress, European officials, senior corporate executives, representatives from multilateral organizations, and experts to evaluate progress and identify current needs. Speakers included Peter van Blyenburgh, President of UVS International; Kenneth “Doug” Davis, UAS Program Office Manager for the U.S. Federal Aviation Administration; Sara Summers, UAS Deputy Project Manager for the U.S. National Oceanic and Atmospheric Administration; Douglas Koupash, Executive Director of Mission Support, Office of CBP Air and Marine, U.S. Customs and Border Protection; and Rear Admiral Wayne Justice, USCG, Assistant Commandant for Capability for the U.S. Coast Guard. Major General Michael Kostelnik, USAF (Ret), Assistant Commissioner for CBP Air and Marine, U.S. Customs and Border Protection presented keynote remarks.